Etoposide-related acute promyelocytic leukemia

被引：39

作者：

Kudo, K

Yoshida, H

Kiyoi, H

Numata, S

Horibe, K

Naoe, T

机构：

[1] Nagoya Univ Hosp, Dept Infect Dis, Showa Ku, Nagoya, Aichi 4668550, Japan

[2] Nagoya Univ Hosp, Dept Infect Dis, Nagoya, Aichi, Japan

来源：

LEUKEMIA | 1998年 / 12卷 / 08期

关键词：

acute promyelocytic leukemia; therapy-related leukemia; etoposide; PML-RAR alpha; Langerhans cell histiocytosis;

D O I：

10.1038/sj.leu.2401089

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The development of therapy-related acute myeloid leukemia (t-AML) has become a growing concern over the past decade, because of the increase in the percentage of long-term survivors of primary malignancy. We reviewed 17 cases with etoposide-related acute promyelocytic leukemia (APL) reported in the literature. The close association between treatment with etoposide for Langerhans cell histiocytosis (LCH) and the development of etoposide-related APL was demonstrated among Japanese and Italians. Our data on the breakpoints (b/ps) of the PML and RAR alpha genes are presented. It is suggested that chromatin structure might be more important than specific consensus sequence in the distribution of b/ps in etoposide-related APL.

引用

收藏

页码：1171 / 1175

页数：5

相关论文

共 44 条

[1] TRANSLOCATION BREAKPOINT OF ACUTE PROMYELOCYTIC LEUKEMIA LIES WITHIN THE RETINOIC ACID RECEPTOR-ALPHA LOCUS [J].

ALCALAY, M ;

ZANGRILLI, D ;

PANDOLFI, PP ;

LONGO, L ;

MENCARELLI, A ;

GIACOMUCCI, A ;

ROCCHI, M ;

BIONDI, A ;

RAMBALDI, A ;

LOCOCO, F ;

DIVERIO, D ;

DONTI, E ;

GRIGNANI, F ;

PELICCI, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (05) :1977-1981

[2] LANGERHANS CELL HISTIOCYTOSIS AND ACUTE-LEUKEMIA - UNUSUAL ASSOCIATION IN 2 CASES [J].

ARICO, M ;

COMELLI, A ;

BOSSI, G ;

RAITERI, E ;

PIOMBO, M ;

EGELER, RM .

MEDICAL AND PEDIATRIC ONCOLOGY, 1993, 21 (04) :271-273

[3] ETOPOSIDE (VP-16-213)-INDUCED GENE ALTERATIONS - POTENTIAL CONTRIBUTION TO CELL-DEATH [J].

BERGER, NA ;

CHATTERJEE, S ;

SCHMOTZER, JA ;

HELMS, SR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) :8740-8743

[4] Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: Correlation with scaffold attachment regions and topoisomerase II consensus binding sites [J].

Broeker, PLS ;

Super, HG ;

Thirman, MJ ;

Pomykala, H ;

Yonebayashi, Y ;

Tanabe, S ;

ZeleznikLe, N ;

Rowley, JD .

BLOOD, 1996, 87 (05) :1912-1922

[5] Etoposide causes illegitimate V(D)J recombination in human lymphoid leukemic cells [J].

Chen, CL ;

Fuscoe, JC ;

Liu, Q ;

Relling, MV .

BLOOD, 1996, 88 (06) :2210-2218

[6] THERAPY-RELATED ACUTE PROMYELOCYTIC LEUKEMIA - A REPORT ON 16 CASES [J].

DETOURMIGNIES, L ;

CASTAIGNE, S ;

STOPPA, AM ;

HAROUSSEAU, JL ;

SADOUN, A ;

JANVIER, M ;

DEMORY, JL ;

SANZ, M ;

BERGER, R ;

BAUTERS, F ;

CHOMIENNE, C ;

FENAUX, P .

JOURNAL OF CLINICAL ONCOLOGY, 1992, 10 (09) :1430-1435

[7]

DORNER PH, 1995, LEUKEMIA, V9, P1305

[8] THERAPY RELATED MYELODYSPLASTIC SYNDROME AND LEUKEMIA WITH NO UNFAVORABLE CYTOGENETIC FINDINGS HAVE A GOOD RESPONSE TO INTENSIVE CHEMOTHERAPY - A REPORT ON 15 CASES [J].

FENAUX, P ;

LAI, JL ;

QUIQUANDON, I ;

PREUDHOMME, C ;

DUPRIEZ, B ;

FACON, T ;

LORTHOIS, C ;

LUCIDARME, D ;

BAUTERS, F .

LEUKEMIA & LYMPHOMA, 1991, 5 (2-3) :117-125

[9]

HAUPT R, 1993, AM J PEDIAT HEMATOL, V15, P255

[10]

Haupt R, 1997, INT J CANCER, V71, P9, DOI 10.1002/(SICI)1097-0215(19970328)71:1<9::AID-IJC3>3.0.CO

← 1 2 3 4 5 →