Chronic obstructive pulmonary disease: new opportunities for drug development

被引：41

作者：

Barnes, PJ ^{[1
]}

机构：

[1] Natl Heart & Lung Inst, Imperial Coll, Sch Med, London SW3 6LY, England

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1998年 / 19卷 / 10期

关键词：

D O I：

10.1016/S0165-6147(98)01245-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Chronic obstructive pulmonary disease (COPD) is common and there is an increasing worldwide prevalence. There are no available treatments to prevent the progression of airflow obstruction, but greater understanding of the molecular and cellular mechanisms involved in COPD has identified many new therapeutic targets, including inflammatory mediators, proteases and adhesion molecules. In this review, Peter Barnes considers potential new drugs for this neglected disease.

引用

页码：415 / 423

页数：9

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