Platelets as targets of snake venom metalloproteinases

被引：78

作者：

Kamiguti, AS ^{[1
]}

机构：

[1] Univ Liverpool, Dept Haematol, Liverpool L69 3GA, Merseyside, England

来源：

TOXICON | 2005年 / 45卷 / 08期

关键词：

haemorrhage; snake venom metalloproteinases; platelet function; collagen receptors; alpha(2)beta(1) integrin;

D O I：

10.1016/j.toxicon.2005.02.026

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

For centuries snake venoms have been known to interfere with haemostasis and this is now known basically due either to toxins activating/inhibiting clotting factors, having effects on blood vessels or interfering with platelet function. In this short review, the interaction of one major group of toxins, the snake venom metalloproteinases, with platelets is considered. This is relevant for understanding the mechanism of haemorrhage induced by these toxins. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1041 / 1049

页数：9

共 70 条

[1]

AHMED NK, 1990, HAEMOSTASIS, V20, P147

[2] A novel viper venom metalloproteinase, alborhagin, is an agonist at the platelet collagen receptor GPVI [J].

Andrews, RK ;

Gardiner, EE ;

Asazuma, N ;

Berlanga, O ;

Tulasne, D ;

Nieswandt, B ;

Smith, AI ;

Berndt, MC ;

Watson, SP .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (30) :28092-28097

[3] CHARACTERIZATION OF A METALLOPROTEINASE FROM BOTHROPS-ASPER (TERCIOPELO) SNAKE-VENOM [J].

ARAGONORTIZ, F ;

GUBENSEK, F .

TOXICON, 1987, 25 (07) :759-766

[4] HEMORRHAGIC METALLOPROTEINASES FROM SNAKE-VENOMS [J].

BJARNASON, JB ;

FOX, JW .

PHARMACOLOGY & THERAPEUTICS, 1994, 62 (03) :325-372

[5] A POTENTIAL FUSION PEPTIDE AND AN INTEGRIN LIGAND DOMAIN IN A PROTEIN ACTIVE IN SPERM-EGG FUSION [J].

BLOBEL, CP ;

WOLFSBERG, TG ;

TURCK, CW ;

MYLES, DG ;

PRIMAKOFF, P ;

WHITE, JM .

NATURE, 1992, 356 (6366) :248-252

[6] BOTROCETIN (VENOM COAGGLUTININ) - REACTION WITH A BROAD-SPECTRUM OF MULTIMERIC FORMS OF FACTOR-VIII MACROMOLECULAR COMPLEX [J].

BRINKHOUS, KM ;

READ, MS ;

FRICKE, WA ;

WAGNER, RH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (05) :1463-1466

[7]

CARDOSO JLC, 1993, Q J MED, V86, P315

[8] A new protein structure of P-II class snake venom metalloproteinases: it comprises metalloproteinase and disintegrin domains [J].

Chen, RQ ;

Jin, Y ;

Wu, JB ;

Zhou, XD ;

Lu, QM ;

Wang, WY ;

Xiong, YL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 310 (01) :182-187

[9] INTEGRIN RECEPTORS ON AORTIC SMOOTH-MUSCLE CELLS MEDIATE ADHESION TO FIBRONECTIN, LAMININ, AND COLLAGEN [J].

CLYMAN, RI ;

MCDONALD, KA ;

KRAMER, RH .

CIRCULATION RESEARCH, 1990, 67 (01) :175-186

[10] BaG, a new dimeric metalloproteinase/disintegrin from the Bothrops alternatus snake venom that interacts with α5β1 integrin [J].

Cominetti, MR ;

Ribeiro, JU ;

Fox, JW ;

Selistre-De-Araujo, HS .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2003, 416 (02) :171-179

← 1 2 3 4 5 6 7 →