Cytotoxic constituents from the roots of Anthriscus sylvestris

被引：38

作者：

Lim, YH

Leem, MJ

Shin, DH

Chang, HB

Hong, SW

Moon, EY

Lee, DK

Yoon, SJ

Woo, WS

机构：

[1] Dong Wha Pharmaceut Ind Co Ltd, R&D Ctr, Anyang 430010, Kyonggi Do, South Korea

[2] Seoul Natl Univ, Inst Nat Prod Res, Seoul 110460, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 1999年 / 22卷 / 02期

关键词：

Anthriscus sylvestris; anti-tumour agents; cytotoxic lignans; angeloyl podophyllotoxin;

D O I：

10.1007/BF02976548

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolation and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the chloroform soluble fraction. tt is the first report of the occurrence of compound 5 in nature.

引用

页码：208 / 212

页数：5

共 11 条

[1]

AYRES DC, 1990, LIGNANS LOGICAL CLIN

[2] AN ASYMMETRIC-SYNTHESIS OF (-)-DEOXYPODOPHYLLOTOXIN [J].