Can novel therapies for arrhythmias caused by spontaneous sarcoplasmic reticulum Ca2+ release be developed using mouse models?

被引：14

作者：

Houser, SR ^{[1
]}

机构：

[1] Temple Univ, Sch Med, Cardiovasc Res Ctr, Philadelphia, PA 19140 USA

来源：

CIRCULATION RESEARCH | 2005年 / 96卷 / 10期

关键词：

cardiac arrhythmias; sarcoplasmic reticulum; ryanodine receptor; calcium regulation; heart failure;

D O I：

10.1161/01.RES.0000168921.55931.63

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1031 / 1032

页数：2

共 17 条

[1] Cardiac excitation-contraction coupling [J].

Bers, DM .

NATURE, 2002, 415 (6868) :198-205

[2] SYNCHRONOUS OCCURRENCE OF SPONTANEOUS LOCALIZED CALCIUM RELEASE FROM THE SARCOPLASMIC-RETICULUM GENERATES ACTION-POTENTIALS IN RAT CARDIAC VENTRICULAR MYOCYTES AT NORMAL RESTING MEMBRANE-POTENTIAL [J].

CAPOGROSSI, MC ;

HOUSER, SR ;

BAHINSKI, A ;

LAKATTA, EG .

CIRCULATION RESEARCH, 1987, 61 (04) :498-503

[3] Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor [J].

Cerrone, M ;

Colombi, B ;

Santoro, M ;

di Barletta, MR ;

Scelsi, M ;

Villani, L ;

Napolitano, C ;

Priori, SG .

CIRCULATION RESEARCH, 2005, 96 (10) :E77-E82

[4] CALCIUM SPARKS - ELEMENTARY EVENTS UNDERLYING EXCITATION-CONTRACTION COUPLING IN HEART-MUSCLE [J].

CHENG, H ;

LEDERER, WJ ;

CANNELL, MB .

SCIENCE, 1993, 262 (5134) :740-744

[5] TIME AND CALCIUM DEPENDENCE OF ACTIVATION AND INACTIVATION OF CALCIUM-INDUCED RELEASE OF CALCIUM FROM THE SARCOPLASMIC-RETICULUM OF A SKINNED CANINE CARDIAC PURKINJE-CELL [J].

FABIATO, A .

JOURNAL OF GENERAL PHYSIOLOGY, 1985, 85 (02) :247-289

[6]

FABIATO A, 1983, AM J PHYSIOL, V245, P1

[7] Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes [J].

George, CH ;

Higgs, GV ;

Lai, FA .

CIRCULATION RESEARCH, 2003, 93 (06) :531-540

[8] RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR) [J].

Jiang, DW ;

Xiao, BL ;

Yang, DM ;

Wang, RW ;

Choi, P ;

Zhang, L ;

Cheng, HP ;

Chen, SRW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (35) :13062-13067

[9] Enhanced basal activity of a cardiac Ca2+ release channel (Ryanodine receptor) mutant associated with ventricular tachycardia and sudden death [J].

Jiang, DW ;

Xiao, BL ;

Zhang, L ;

Chen, SRW .

CIRCULATION RESEARCH, 2002, 91 (03) :218-225

[10] FUNCTIONAL IMPLICATIONS OF SPONTANEOUS SARCOPLASMIC-RETICULUM CA2+ RELEASE IN THE HEART [J].

LAKATTA, EG .

CARDIOVASCULAR RESEARCH, 1992, 26 (03) :193-214

← 1 2 →