Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia

被引：32

作者：

Rodriguez-Barraquer, Isabel ^{[1
]}

Gongora, Rafael ^{[1
]}

Prager, Martin ^{[1
]}

Pacheco, Robinson ^{[1
]}

Montero, Luz Mery ^{[2
]}

Navas, Adriana ^{[1
]}

Ferro, Cristina ^{[3
]}

Miranda, Maria Consuelo ^{[1
]}

Saravia, Nancy G. ^{[1
]}

机构：

[1] Ctr Int Entrenamiento & Invest Med, Cali, Colombia

[2] Hosp San Juan Bautista Chaparral, Tolima, Colombia

[3] Inst Nacl Salud, Bogota, DC, Colombia

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2008年 / 78卷 / 02期

关键词：

D O I：

10.4269/ajtmh.2008.78.276

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

American cutaneous leishmaniasis (ACL) has been characterized as a zoonotic disease. However, peri-domestic and domestic transmission have been recorded in at least nine countries in Central and South America. The present study was undertaken to identify the etiologic agent of a peridomestic epidemic of ACL in the Department of Tolima, Colombia. Leishmania isolates were obtained during the diagnosis of 56 patients with ACL who consulted the local leishmaniasis control program in three municipalities in Tolima. Species were identified using monoclonal antibodies and isoenzyme electrophoresis. A total of 53 (94.6%) of 56 isolates were identified as Leishmania (Viannia) guyanensis. Three isolates (5.4%) were identified as L. (V) panamensis. Leishmania (V.) guyanensis is the probable etiologic agent of the largest epidemic of cutaneous leishmaniasis recorded in Colombia. This species has not previously been reported outside the Amazon and southeastern regions of Colombia, and has not been described in the peridomestic setting or linked with an epidemic.

引用

页码：276 / 282

页数：7

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