Symptom correlates of attentional improvement following hospitalization for a first episode of affective psychosis

被引:36
作者
Sax, KW
Strakowski, SM
Keck, PE
McElroy, SL
West, SA
Stanton, SP
机构
[1] Univ Cincinnati, Dept Psychiat, Psychot Disorders Res Program, Coll Med, Cincinnati, OH 45267 USA
[2] Univ Cincinnati, Dept Psychiat, Biol Psychiat Program, Coll Med, Cincinnati, OH 45267 USA
关键词
attention; affective psychosis; symptom correlates;
D O I
10.1016/S0006-3223(97)00528-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Background: This study examined patients with a first-episode of affective psychosis during acute and compensated states in order to determine whether changes in attentional functioning over rime were accompanied by changes in the severity of psychotic or affective symptoms. Methods: Attentional performance was measured in patients (n = 27) using the degraded-stimulus Continuous Performance Test (CPT) and symptoms were assessed at the time of index hospitalization, and 2 months after discharge. A comparison group of normal volunteers (n 31) also performed the CPT two months apart. Results: Patients performed significantly worse than controls at the initial testing but nor at follow-lip, The improvement in attentional performance significantly correlated with decreased severity of manic symptoms. Conclusions: Results suggest attentional dysfunction is a state-dependent characteristic of mania, and may provide an additional measure of clinical improvement following treatment. Biol Psychiatry 1998;44:784-786 (C) 1998 Society of Biological Psychiatry.
引用
收藏
页码:784 / 786
页数:3
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