Chapter 19. DPP-IV inhibition and therapeutic potential

被引:49
作者
Villhauer, EB [1 ]
Coppola, GM [1 ]
Hughes, TE [1 ]
机构
[1] Novartis Inst Biomed Res, Summit, NJ 07901 USA
来源
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 36 | 2001年 / 36卷
关键词
D O I
10.1016/S0065-7743(01)36059-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:191 / 200
页数:10
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共 139 条
[91]   A MARKER FOR NEOPLASTIC PROGRESSION OF HUMAN MELANOCYTES IS A CELL-SURFACE ECTOPEPTIDASE [J].
MORRISON, ME ;
VIJAYASARADHI, S ;
ENGELSTEIN, D ;
ALBINO, AP ;
HOUGHTON, AN .
JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (04) :1135-1143
[92]  
MRESTANIKLAUS C, 1998, P EUR PEPT S, V24, P661
[93]   Glucagon-like peptide 1 (GLP-1): a potent gut hormone with a possible therapeutic perspective [J].
Nauck, MA .
ACTA DIABETOLOGICA, 1998, 35 (03) :117-129
[94]   Is glucagon-like peptide 1 an incretin hormone? [J].
Nauck, MA .
DIABETOLOGIA, 1999, 42 (03) :373-379
[95]   Specific and irreversible cyclopeptide inhibitors of dipeptidyl peptidase IV activity of the T-cell activation antigen CD26 [J].
Nguyen, C ;
Blanco, J ;
Mazaleyrat, JP ;
Krust, B ;
Callebaut, C ;
Jacotot, E ;
Hovanessian, AG ;
Wakselman, M .
JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (12) :2100-2110
[96]   Mouse fibroblast-activation protein -: Conserved Fap gene organization and biochemical function as a serine protease [J].
Niedermeyer, J ;
Enenkel, B ;
Park, JE ;
Lenter, M ;
Rettig, WJ ;
Damm, K ;
Schnapp, A .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 254 (03) :650-654
[97]   Targeted disruption of mouse fibroblast activation protein [J].
Niedermeyer, J ;
Kriz, M ;
Hilberg, F ;
Garin-Chesa, P ;
Bamberger, U ;
Lenter, MC ;
Park, J ;
Viertel, B ;
Püschner, H ;
Mauz, M ;
Rettig, WJ ;
Schnapp, A .
MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (03) :1089-1094
[98]   TMC-2A, -2B and -2C, novel dipeptidyl peptidase IV inhibitors produced by Aspergillus oryzae A374 .1. Taxonomy of producing strain, fermentation, and biochemical properties [J].
Nonaka, N ;
Asai, Y ;
Nishio, M ;
Takahashi, K ;
Okuda, T ;
Tanaka, S ;
Sugita, T ;
Ohnuki, T ;
Komatsubara, S .
JOURNAL OF ANTIBIOTICS, 1997, 50 (08) :646-652
[99]  
OGATA S, 1989, J BIOL CHEM, V264, P3596
[100]   Inhibition of dipeptidyl peptidase IV (CD26) by peptide boronic acid dipeptides [J].
Pargellis, CA ;
Campbell, SJ ;
Pav, S ;
Graham, ET ;
Pitner, TP .
JOURNAL OF ENZYME INHIBITION, 1997, 11 (03) :151-169