Designer emulsions using microfluidics

被引：647

作者：

Shah, Rhutesh K. ^{[1
]}

Shum, Ho Cheung ^{[1
]}

Rowat, Amy C. ^{[1
]}

Lee, Daeyeon ^{[1
]}

Agresti, Jeremy J. ^{[1
]}

Utada, Andrew S. ^{[1
]}

Chu, Liang-Yin ^{[1
,2
]}

Kim, Jin-Woong ^{[1
,3
]}

Fernandez-Nieves, Alberto ^{[1
,4
]}

Martinez, Carlos J. ^{[1
,5
]}

Weitz, David A. ^{[1
,6
]}

机构：

[1] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA

[2] Sichuan Univ, Sch Chem Engn, Chengdu 610065, Peoples R China

[3] Amore Pacific R&D Ctr, Yongin 446729, South Korea

[4] Georgia Inst Technol, Sch Phys, Atlanta, GA 30332 USA

[5] Purdue Univ, Sch Mat Engn, W Lafayette, IN 47907 USA

[6] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA

来源：

MATERIALS TODAY | 2008年 / 11卷 / 04期

关键词：

D O I：

10.1016/S1369-7021(08)70053-1

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We describe new developments for the controlled fabrication of monodisperse emulsions using microfluidics. We use glass capillary devices to generate single, double, and higher order emulsions with exceptional precision. These emulsions can serve as ideal templates for generating well-defined particles and functional vesicles. Polydimethylsiloxane microfluidic devices are also used to generate picoliter-scale water-in-oil emulsions at rates as high as 10 000 drops per second. These emulsions have great potential as individual microvessels in high-throughput screening applications, where each drop serves to encapsulate single cells, genes, or reactants.

引用

页码：18 / 27

页数：10

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