BAG3 protein regulates stress-induced apoptosis in normal and neoplastic leukocytes

被引:85
作者
Bonelli, P
Petrella, A
Rosati, A
Romano, MF
Lerose, R
Pagliuca, MG
Amelio, T
Festa, M
Martire, G
Venuta, S
Turco, MC [1 ]
Leone, A
机构
[1] Univ Salerno, Dipartimento Sci Farmaceut, Salerno, Italy
[2] Tumour Inst Fdn Sen Pascale, Naples, Italy
[3] Univ Naples Federico II, Dipartimento Biochim & Biotecnol Med, Naples, Italy
[4] Univ Naples Federico II, Area Ematol, Naples, Italy
[5] Univ Molise, Dipartimento Sci & Tecnol Ambiente & Terr, Campobasso, Italy
[6] Univ Catanzaro, Dipartimento Med Sperimentale & Clin, Catanzaro, Italy
关键词
D O I
10.1038/sj.leu.2403219
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:358 / 360
页数:3
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共 21 条
  • [1] Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein
    Antoku, K
    Maser, RS
    Scully, WJ
    Delach, SM
    Johnson, DE
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 286 (05) : 1003 - 1010
  • [2] Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
    Beere, HM
    Wolf, BB
    Cain, K
    Mosser, DD
    Mahboubi, A
    Kuwana, T
    Tailor, P
    Morimoto, RI
    Cohen, GM
    Green, DR
    [J]. NATURE CELL BIOLOGY, 2000, 2 (08) : 469 - 475
  • [3] BEERE HM, 2001, SCI STKE, V93, pRE1
  • [4] ROS, stress-activated kinases and stress signaling in cancer
    Benhar, M
    Engelberg, D
    Levitzki, A
    [J]. EMBO REPORTS, 2002, 3 (05) : 420 - 425
  • [5] Heat shock protein 70 inhibits caspase-dependent and -independent apoptosis in Jurkat T cells
    Creagh, EM
    Carmody, RJ
    Cotter, TG
    [J]. EXPERIMENTAL CELL RESEARCH, 2000, 257 (01) : 58 - 66
  • [6] What's in the 'BAG'? - a functional domain analysis of the BAG-family proteins
    Doong, H
    Vrailas, A
    Kohn, EC
    [J]. CANCER LETTERS, 2002, 188 (1-2) : 25 - 32
  • [7] CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation - Accumulation of poly-ubiquitinated Hsp90 client proteins
    Doong, H
    Rizzo, K
    Fang, SY
    Kulpa, V
    Weissman, AM
    Kohn, EC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (31) : 28490 - 28500
  • [8] CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-γ and Hsp70/Hsc70
    Doong, H
    Price, J
    Kim, YS
    Gasbarre, C
    Probst, J
    Liotta, LA
    Blanchette, J
    Rizzo, K
    Kohn, E
    [J]. ONCOGENE, 2000, 19 (38) : 4385 - 4395
  • [9] Cellular stress response and apoptosis in cancer therapy
    Herr, I
    Debatin, KM
    [J]. BLOOD, 2001, 98 (09) : 2603 - 2614
  • [10] Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases
    Jäättelä, M
    Wissing, D
    Kokholm, K
    Kallunki, T
    Egeblad, M
    [J]. EMBO JOURNAL, 1998, 17 (21) : 6124 - 6134