Effects of prism adaptation on motor-intentional spatial bias in neglect

被引:56
作者
Fortis, Paola [1 ,2 ,3 ]
Chen, Peii [3 ,4 ,5 ]
Goedert, Kelly M. [8 ]
Barrett, Anna M. [3 ,4 ,5 ,6 ,7 ,9 ]
机构
[1] Univ Milano Bicocca, Dept Psychol, I-20126 Milan, Italy
[2] IRCCS Italian Auxol Inst, Neuropsychol Lab, Milan, Italy
[3] Kessler Fdn Res Ctr, W Orange, NJ USA
[4] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Phys Med & Rehabil, W Orange, NJ 07052 USA
[5] Univ Med & Dent New Jersey, New Jersey Med Sch, Grad Sch Biomed Sci, W Orange, NJ 07052 USA
[6] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Neurol & Neurosci, W Orange, NJ 07052 USA
[7] Kessler Inst Rehabil, W Orange, NJ USA
[8] Seton Hall Univ, Dept Psychol, S Orange, NJ 07079 USA
[9] Kessler Inst Rehabil, Saddle Brook, NJ USA
关键词
motor neglect; prism adaptation; rehabilitation; sensory neglect; spatial neglect; JUDGMENTS; VOLUNTARY;
D O I
10.1097/WNR.0b013e32834a3e20
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
Prism adaptation may alleviate some symptoms of spatial neglect. However, the mechanism through which this technique works is still unclear. This study investigated whether prism adaptation differentially affects dysfunction in perceptual-attentional 'where' bias versus motor-intentional 'aiming' bias. Five neglect patients performed a line bisection task in which lines were viewed under both normal and right-left reversed viewing conditions, allowing for the fractionation of 'where' and 'aiming' spatial bias components. After two consecutive days of prism adaptation, participants demonstrated a significant improvement in 'aiming' spatial bias, with no effect on 'where' spatial bias. These findings suggest that prism adaptation may primarily affect motor-intentional 'aiming' bias in poststroke spatial neglect patients. NeuroReport 22:700-705 (C) 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
引用
收藏
页码:700 / 705
页数:6
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