Application of magnetic liposomes for magnetically guided transport of muscle relaxants and anti-cancer photodynamic drugs

被引：77

作者：

Kuznetsov, AA

Filippov, VI

Alyautdin, RN

Torshina, NL

Kuznetsov, OA

机构：

[1] Univ Louisiana Lafayette, Lafayette, LA 70504 USA

[2] Russian Acad Sci, Inst Biochem Phys, Moscow 117977, Russia

[3] Moscow Med Acad, Moscow, Russia

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2001年 / 225卷 / 1-2期

关键词：

magnetic liposomes; muscle relaxants; photosensitizer; catalytic sensitizer; anesthesis; oncology; magnetic drug targeting; diadony; diperony; photosense; metal phthalocyanine; liposomes; teraphthal;

D O I：

10.1016/S0304-8853(00)01235-X

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Magnetic liposomes containing submicron-sized ferromagnetic particles were prepared encapsulating the muscle relaxant drugs, diadony or diperony, for local anesthesia. Alternatively, metal phthalocyanines (Photosense or Teraphthal), sensitizers for photodynamic or catalytic cancer therapy were loaded into the magnetic liposomes. Animal trials demonstrated successful magnetically guided transport of the drug-loaded liposomes. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：95 / 100

页数：6

共 17 条

[1]

ALYAUTDIN RN, 1983, NEW MYORELAXANTS KHA

[2]

Babincova M, 1995, PHARMAZIE, V50, P828

[3] TRAPPING OF DEXTRAN-COATED COLLOIDS IN LIPOSOMES BY TRANSIENT BINDING TO AMINOPHOSPHOLIPID - PREPARATION OF FERROSOMES [J].