Poly (glutamic acid) - An emerging biopolymer of commercial interest

被引：285

作者：

Bajaj, Ishwar ^{[1
]}

Singhal, Rekha ^{[1
]}

机构：

[1] Inst Chem Technol, Food Engn & Technol Dept, Bombay 400019, Maharashtra, India

来源：

BIORESOURCE TECHNOLOGY | 2011年 / 102卷 / 10期

关键词：

Poly (gamma-glutamic acid); Biosynthesis; Biopolymer; Bacillus; Fermentation; GAMMA-POLYGLUTAMIC ACID; SOLID-STATE FERMENTATION; LICHENIFORMIS NCIM 2324; BACILLUS-SUBTILIS; POLY(GAMMA-GLUTAMIC ACID); POLY(GLUTAMIC ACID); ENHANCED PRODUCTION; COVALENT IMMOBILIZATION; EFFICIENT PRODUCTION; BATCH FERMENTATION;

D O I：

10.1016/j.biortech.2011.02.047

中图分类号：

S2 [农业工程];

学科分类号：

082806 [农业信息与电气工程];

摘要：

Poly (gamma-glutamic acid) (PGA) is water-soluble, anionic, biodegradable, and edible biopolymer produced by Bacillus subtilis. It has multifarious potential applications in foods, pharmaceuticals, healthcare, water treatment and other fields. The production of PGA has already been established on the industrial scale. Various studies regarding the fermentative production, downstream processing and characterization of PGA have been reported in the literature. This review provides updated information on fermentative production of PGA by various bacterial strains and effect of fermentation conditions and media component on production of PGA in submerged as well as solid state fermentation. Information on the application of genetic engineering for enhancement of yield of PGA, kinetic studies for production of PGA in submerged fermentation and recovery and purification of PGA is included. An attempt has also been made to review the current and potential applications of PGA. This review may contribute to further development of this commercially and academically interesting biopolymer. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5551 / 5561

页数：11

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