Hydroxyurea for the treatment of sickle cell anemia

被引：275

作者：

Platt, Orah S. ^{[1
]}

机构：

[1] Childrens Hosp, Dept Lab Med, Boston, MA 02115 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2008年 / 358卷 / 13期

关键词：

D O I：

10.1056/NEJMct0708272

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An 18-year-old woman with sickle cell anemia presents with recurrent painful crises, and treatment with hydroxyurea is recommended. Hydroxyurea causes a shift toward the production of red cells containing fetal hemoglobin. A possible increase in the risk of acute leukemia due to hydroxyurea therapy remains the subject of debate. Copyright © 2008 Massachusetts Medical Society.

引用

页码：1362 / 1369

页数：8

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