Protocol biopsies in renal transplantation: research tool or clinically useful?

被引:36
作者
Rush, DN
Nickerson, P
Jeffery, JR
McKenna, RM
Grimm, PC
Gough, J
机构
[1] Hlth Sci Ctr, Dept Med, Winnipeg, MB R3A 1R9, Canada
[2] Hlth Sci Ctr, Dept Immunol, Winnipeg, MB, Canada
[3] Hlth Sci Ctr, Dept Pediat, Winnipeg, MB, Canada
[4] Hlth Sci Ctr, Dept Pathol, Winnipeg, MB, Canada
[5] Univ Manitoba, Winnipeg, MB, Canada
关键词
D O I
10.1097/00041552-199811000-00012
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Early protocol biopsies of stable, well functioning renal allografts reveal a high prevalence of clinically unsuspected acute and chronic pathology. It is becoming increasingly apparent that these histopathological findings are both pathogenic and predictive of long-term allograft outcome. Therefore, protocol biopsies may be required for optimal post-transplant surveillance until non-invasive methods to detect allograft inflammation are developed. (C) 1998 Lippincott Williams & Wilkins.
引用
收藏
页码:691 / 694
页数:4
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