Nitrated cyclic GMP as a new cellular signal

被引：11

作者：

Feelisch, Martin ^{[1
]}

机构：

[1] Univ Warwick, Warwick Med Sch, Clin Sci Res Inst, Coventry CV4 7AL, W Midlands, England

来源：

NATURE CHEMICAL BIOLOGY | 2007年 / 3卷 / 11期

关键词：

D O I：

10.1038/nchembio1107-687

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Nitric oxide–mediated production of cyclic guanosine 3′,5′-monophosphate (cGMP) is a crucial signal transduction pathway that controls a wide array of biological functions. A new layer of complexity in mammalian cell regulation is revealed by the discovery of a redox-active nitrated cGMP derivative with the ability to post-translationally modify protein thiol residues by S-guanylation.

引用

页码：687 / 688

页数：2

共 7 条

[1]

Nitro-fatty acid reaction with glutathione and cysteine - Kinetic analysis of thiol alkylation by a Michael addition reaction [J].

Baker, Laura M. S. ;

Baker, Paul R. S. ;

Golin-Bisello, Franca ;

Schopfer, Francisco J. ;

Fink, Mitchell ;

Woodcock, Steven R. ;

Branchaud, Bruce P. ;

Radi, Rafael ;

Freeman, Bruce A. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (42) :31085-31093

[2]

Cyclic nucleotide research - still expanding after half a century [J].

Beavo, JA ;

Brunton, LL .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (09) :710-718

[3]

Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues [J].

Bryan, NS ;

Fernandez, BO ;

Bauer, SM ;

Gauria-Saura, MF ;

Milsom, AB ;

Rassaf, T ;

Maloney, RE ;

Bharti, A ;

Rodriguez, J ;

Feelisch, M .

NATURE CHEMICAL BIOLOGY, 2005, 1 (05) :290-297

[4]

THE EARLY ROLE OF NITRIC-OXIDE IN EVOLUTION [J].

FEELISCH, M ;

MARTIN, JF .

TRENDS IN ECOLOGY & EVOLUTION, 1995, 10 (12) :496-499

[5]

Protein S-guanylation by the biological signal 8-nitroguanosine 3′,5′-cyclic monophosphate [J].

Sawa, Tomohiro ;

Zaki, Mohammad Hasan ;

Okamoto, Tatsuya ;

Akuta, Teruo ;

Tokutomi, Yoshiko ;

Kim-Mitsuyama, Shokei ;

Ihara, Hideshi ;

Kobayashi, Akira ;

Yamamoto, Masayuki ;

Fujii, Shigemoto ;

Arimoto, Hirokazu ;

Akaike, Takaaki .

NATURE CHEMICAL BIOLOGY, 2007, 3 (11) :727-735

[6]

Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway [J].

Villacorta, Luis ;

Zhang, Jifeng ;

Garcia-Barrio, Minerva T. ;

Chen, Xi-lin ;

Freeman, Bruce A. ;

Chen, Yuqing E. ;

Cui, Taixing .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2007, 293 (01) :H770-H776

[7]

Wink DA, 2000, HANDB EXP PHARMACOL, V143, P7

← 1 →