New ent-kaurene-type diterpenoids possessing cytotoxicity from the New Zealand liverwort Jungermannia species

被引：28

作者：

Nagashima, F

Kasai, W

Kondoh, M

Fujii, M

Watanabe, Y

Braggins, JE

Asakawa, Y ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan

[2] Showa Pharmaceut Univ, Dept Pharmaceut & Biopharmaceut, Machida, Tokyo 1948543, Japan

[3] Univ Auckland, Sch Biol Sci, Auckland 1, New Zealand

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2003年 / 51卷 / 10期

关键词：

Jungemannia species; liverwort; ent-kaurene; diterpenoid; cytotoxicity; HL-60; cell;

D O I：

10.1248/cpb.51.1189

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new ent-kaurene-type and a new rearranged ent-kaurene-type diterpenoids possessing cytotoxicity against a human leukemia cell line have been isolated from the New Zealand liverwort Jungermannia species, together with previously known ent-kaurene-type diterpenoids. Their structures were established based on extensive NMR techniques.

引用

页码：1189 / 1192

页数：4

共 13 条

[1] Recent advances in phytochemistry of bryophytes-acetogenins, terpenoids and bis(bibenzyl)s from selected Japanese, Taiwanese, New Zealand, Argentinean and European liverworts [J].