Beam me up, Scottie! TREK channels swing both ways

被引：5

作者：

Maylie, J

Adelman, JP

机构：

[1] Oregon Hlth Sci Univ, Vollum Inst, Portland, OR 97201 USA

[2] Oregon Hlth Sci Univ, Dept Obstet & Gynecol, Portland, OR 97201 USA

来源：

NATURE NEUROSCIENCE | 2001年 / 4卷 / 05期

关键词：

D O I：

10.1038/87402

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

TREK1 was known as a voltage-independent 'background' potassium channel, but a new study suggests that protein kinase A can reversibly convert it to a voltage-dependent state.

引用

页码：457 / 458

页数：2

共 14 条

[1] BACKGROUND POTASSIUM CURRENT ACTIVE DURING THE PLATEAU OF THE ACTION-POTENTIAL IN GUINEA-PIG VENTRICULAR MYOCYTES [J].

BACKX, PH ;

MARBAN, E .

CIRCULATION RESEARCH, 1993, 72 (04) :890-900

[2] KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel [J].

Bockenhauer, D ;

Zilberberg, N ;

Goldstein, SAN .

NATURE NEUROSCIENCE, 2001, 4 (05) :486-491

[3] An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells [J].

Buckler, KJ ;

Williams, BA ;

Honore, E .

JOURNAL OF PHYSIOLOGY-LONDON, 2000, 525 (01) :135-142

[4] PRESYNAPTIC FACILITATION AS A MECHANISM FOR BEHAVIORAL SENSITIZATION IN APLYSIA [J].

CASTELLUCCI, V ;

KANDEL, ER .

SCIENCE, 1976, 194 (4270) :1176-1178

[5] DOES SUBSTANCE-P MEDIATE SLOW SYNAPTIC EXCITATION WITHIN MYENTERIC PLEXUS [J].

KATAYAMA, Y ;

NORTH, RA .

NATURE, 1978, 274 (5669) :387-388

[6] MECHANISM OF CALCIUM CURRENT MODULATION UNDERLYING PRESYNAPTIC FACILITATION AND BEHAVIORAL SENSITIZATION IN APLYSIA [J].

KLEIN, M ;

KANDEL, ER .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (11) :6912-6916

[7] Molecular and functional properties of two-pore-domain potassium channels [J].

Lesage, F ;

Lazdunski, M .

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2000, 279 (05) :F793-F801

[8] TREK-1 is a heat-activated background K+ channel [J].

Maingret, F ;

Lauritzen, I ;

Patel, AJ ;

Heurteaux, C ;

Reyes, R ;

Lesage, F ;

Lazdunski, M ;

Honoré, E .

EMBO JOURNAL, 2000, 19 (11) :2483-2491

[9] A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons [J].

Millar, JA ;

Barratt, L ;

Southan, AP ;

Page, KM ;

Fyffe, REW ;

Robertson, B ;

Mathie, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (07) :3614-3618

[10] Potassium-channel closure taken to TASK [J].

North, RA .

TRENDS IN NEUROSCIENCES, 2000, 23 (06) :234-235

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