Mooren's ulcer

Mooren's ulcer of the cornea, also known as chronic serpiginous ulcer and ulcus rodens, was first described by Bowman in 1849 [1]. Mooren, in 1867, published cases describing the disorder in detail and establishing it as a distinct clinical entity [1]. Mooren's ulcer is a painful, relentless, chronic ulcerative keratitis that begins peripherally and progresses circumferentially and centrally. It is, by definition, idiopathic, meaning that it occurs in the absence of any systemic disorder to which an ulcerative keratitis may be attributed. Its exact pathophysiology remains uncertain. Advances have been made in the management of this disorder, but a significant percentage of cases remain refractory to available therapies and result in severe visual morbidity.