Prolonged postictal psychosis with forced normalization (Landolt) in temporal lobe epilepsy

被引:17
作者
Akanuma, N [1 ]
Kanemoto, K
Adachi, N
Kawasaki, J
Ito, M
Onuma, T
机构
[1] Natl Ctr Neurol & Psychiat, Dept Psychiat, Natl Ctr Hosp Mental Nervous & Muscular Disorders, Tokyo, Japan
[2] Kings Coll London, Dept Clin Neurosci, Guys Kings & St Thomas Sch Med, London WC2R 2LS, England
[3] Natl Utano Hosp, Dept Psychiat, Kyoto, Japan
[4] Aichi Med Univ, Dept Psychiat, Nagakute, Aichi 48011, Japan
[5] Adachi Mental Clin, Sapporo, Hokkaido, Japan
[6] Musashino Kokubinji Clin, Kokubunji, Tokyo, Japan
关键词
postictal psychosis; temporal lobe epilepsy; prolonged episode; forced normalization;
D O I
10.1016/j.yebeh.2005.01.013
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
We report two patients with temporal lobe epilepsy who developed prolonged episodes of postictal psychosis (>= 12 weeks) following a bout of seizures and a lucid interval. No drug toxicity was noted, and no recurrent or continuous seizures were observed during their prolonged psychotic episodes. Repeated EEGs during the period of psychosis showed that their habitual focal epileptiform abnormalities had disappeared. Responses to neuroleptic treatments were not remarkable. Their psychotic symptoms gradually dispelled after their epileptiform abnormalities reappeared. These observations may suggest possible overlapping mechanisms between a prolongation of psychosis and suppression of epileptiform discharges on a scalp EEG. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:456 / 459
页数:4
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