Platinum (II) complex with cyclometalating 2-phenylpyridine ligand showing high cytotoxicity against cisplatin-resistant cell

被引：31

作者：

El-Mehasseb, IM

Kodaka, M

Okada, T

Tomohiro, T

Okamoto, K

Okuno, H

机构：

[1] Natl Inst Biosci & Human Technol, Dept Biomol, Tsukuba, Ibaraki 3058566, Japan

[2] Univ Tsukuba, Dept Chem, Ibaraki, Osaka 3050006, Japan

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 2001年 / 84卷 / 1-2期

基金：

欧盟地平线“2020”; 英国医学研究理事会;

关键词：

platinum (II) complex; 2-phenylpyridine; cytotoxicity;

D O I：

10.1016/S0162-0134(00)00211-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A platinum (II) mononuclear complex with two kinds of 2-phenylpyridine which coordinate as cyclometalated and non-chelated ligands shows high cytotoxicity against cisplatin-resistant mouse sarcoma 180 cell in comparison with its related complexes. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：157 / 158

页数：2

共 8 条

[1] STRENGTH OF PLATINUM-CARBON SIGMA-BOND IN COMPLEX (ET3P)2PTPH2 [J].