Lactobacillus helveticus fermented milk reduces arterial stiffness in hypertensive subjects

被引:49
作者
Jauhiainena, T.
Ronnback, M.
Vapaatalo, H.
Wuolle, K.
Kautiainen, H.
Korpela, R. [1 ]
机构
[1] Univ Helsinki, Inst Biomed Pharmacol, Helsinki, Finland
[2] Valio Ltd Res & Dev, Helsinki, Finland
[3] Univ Helsinki, Folkhalsan Res Ctr, Helsinki, Finland
[4] Reumatism Fdn, Heinola, Finland
关键词
arterial stiffness; AASI; hypertension; ambulatory blood pressure measurement; biologically active tripeptides; Lactobacillus helveticus;
D O I
10.1016/j.idairyj.2007.03.002
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The present study evaluated the 10-week-treatment effect of Lactobacillus helveticus fermented milk containing the tripeptides isoleucyl-prolyl-proline (lie-Pro-Pro) and valyl-prolyl-proline (Val-Pro-Pro) on ambulatory arterial stiffness index (AASI) by using the ambulatory 24-h blood pressure registration. The AASI improved significantly in the peptide milk group (p = 0.043), but not in the placebo group (p = 0.47), suggesting a mechanism for the antihypertensive effects of these peptides. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1209 / 1211
页数:3
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