Catalysis of aldehyde and imine silylcyanation by platinum and palladium NCN-pincer complexes

被引：53

作者：

Fossey, JS ^{[1
]}

Richards, CJ ^{[1
]}

机构：

[1] Univ London Queen Mary & Westfield Coll, Dept Chem, London E1 4NS, England

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 49期

关键词：

silylcyanation; catalysis; pincer complexes; LEWIS-ACID CATALYST; ALDIMINE;

D O I：

10.1016/j.tetlet.2003.09.201

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The room temperature addition of trimethylsilylcyanide to aromatic and aliphatic aldehydes to give the corresponding cyanohydrins is efficiently catalysed by 1 mol% of ((2,6-bis(N-cyclohexyl)imino)phenyl)aquoplatinum(II) trifluoromethanesulfonate 1a. This methodology is also applicable to the addition of trimethylsilylcyanide to Schiff bases resulting in the formation of alpha-amino nitriles. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8773 / 8776

页数：4

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