Aminoacyl-tRNA synthetase gene regulation in Bacillus subtilis

被引：18

作者：

Condon, C ^{[1
]}

GrunbergManago, M ^{[1
]}

Putzer, H ^{[1
]}

机构：

[1] INST BIOL PHYSICOCHIM,UPR 9073,F-75005 PARIS,FRANCE

来源：

BIOCHIMIE | 1996年 / 78卷 / 06期

关键词：

aminoacyl-tRNA synthetase; antitermination; tRNA; processing; Bacillus subtilis;

D O I：

10.1016/0300-9084(96)84744-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this review, we summarize progress on the regulation of the aminoacyl-tRNA synthetase genes in Bacillus subtilis. Most of the genes encoding this set of enzymes in B subtilis are members of a large family of Gram-positive genes and operons controlled by a novel antitermination mechanism that uses their cognate uncharged tRNA as the effector. A subset of these genes is, in addition, likely to be controlled at the level of mRNA processing and degradation. We describe the key experiments leading to these conclusions.

引用

页码：381 / 389

页数：9

共 54 条

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