Survival of Mycobacterium ulcerans at 37°C

被引:22
作者
Eddyani, M. [1 ]
Portaels, F. [1 ]
机构
[1] Inst Trop Med, Dept Microbiol, Mycobacteriol Unit, B-2000 Antwerp, Belgium
关键词
buruli ulcer; geographical origin; Mycobacterium ulcerans; survival; thermotolerance;
D O I
10.1111/j.1469-0691.2007.01791.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Bone infection and metastatic spread in cases of Buruli ulcer imply that Mycobacterium ulcerans is able to survive and multiply at 37 degrees C. This study investigated the survival at 37 degrees C of M. ulcerans isolates from diverse geographical and clinical sources. Although the viability of all isolates decreased after a few days at 37 degrees C, viable bacilli remained after 13 days at 37 degrees C in most instances. African isolates of M. ulcerans were more thermotolerant than isolates from temperate regions. Isolates from skin and bone lesions of the same patients showed no difference in thermotolerance.
引用
收藏
页码:1033 / 1035
页数:4
相关论文
共 16 条
[1]   Evaluation of PCR-restriction profile analysis and IS2404 restriction fragment length polymorphism and amplified fragment length polymorphism fingerprinting for identification and typing of Mycobacterium ulcerans and M-marinum [J].
Chemlal, K ;
Huys, G ;
Fonteyne, PA ;
Vincent, V ;
Lopez, AG ;
Rigouts, L ;
Swings, J ;
Meyers, WM ;
Portaels, F .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (09) :3272-3278
[2]   The use of IS2404 restriction fragment length polymorphisms suggests the diversity of Mycobacterium ulcerans from different geographical areas [J].
Chemlal, K ;
De Ridder, K ;
Fonteyne, PA ;
Meyers, WM ;
Swings, J ;
Portaels, E .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2001, 64 (5-6) :270-273
[3]   Mycobacterium ulcerans disease (Buruli ulcer) in rural hospital, southern Benin, 1997-2001 [J].
Debacker, M ;
Aguiar, J ;
Steunou, C ;
Zinsou, C ;
Meyers, WM ;
Guédénon, A ;
Scott, JT ;
Dramaix, M ;
Portaels, F .
EMERGING INFECTIOUS DISEASES, 2004, 10 (08) :1391-1398
[4]   Evaluation of amplified fragment length polymorphism analysis for inter- and intraspecific differentiation of Mycobacterium bovis, M-tuberculosis, and M-ulcerans [J].
Huys, G ;
Rigouts, L ;
Chemlal, K ;
Portaels, F ;
Swings, J .
JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (10) :3675-3680
[5]  
Johnson PDR, 2005, PLOS MED, V2, P282, DOI 10.1371/journal.pmed.0020108
[6]  
Lagarrigue V, 2000, Med Trop (Mars), V60, P262
[7]   HEAT-TREATMENT OF MYCOBACTERIUM-ULCERANS INFECTIONS WITHOUT SURGICAL EXCISION [J].
MEYERS, WM ;
SHELLY, WM ;
CONNOR, DH .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1974, 23 (05) :924-929
[8]   Heterogeneity of mycolactones produced by clinical isolates of Mycobacterium ulcerans:: Implications for virulence [J].
Mve-Obiang, A ;
Lee, RE ;
Portaels, F ;
Small, PLC .
INFECTION AND IMMUNITY, 2003, 71 (02) :774-783
[9]  
Portaels F., 2003, Bulletin des Seances, Academie Royale des Sciences d'Outre- Mer, V49, P161
[10]   Variability in 3' end of 16S rRNA sequence of Mycobacterium ulcerans is related to geographic origin of isolates [J].
Portaels, F ;
Fonteyne, PA ;
DeBeenhouwer, H ;
DeRijk, P ;
Guedenon, A ;
Hayman, J ;
Meyers, WM .
JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (04) :962-965