Efficient preparation of trisubstituted alkenes using the Julia-Lythgoe olefination of ketones. On the key-role of SmI2 in the reductive elimination step.

被引：46

作者：

Marko, IE ^{[1
]}

Murphy, F ^{[1
]}

Dolan, S ^{[1
]}

机构：

[1] GLAXO WELLCOME MED RES CTR,STEVENAGE SG1 2NY,HERTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 12期

关键词：

D O I：

10.1016/0040-4039(96)00200-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Modification of the Julia-Lythgoe olefination reaction between ketones and primary sulfones leads to trisubstituted alkenes in good overall yields. Samarium diiodide is shown to play a crucial role in the reductive elimination step.

引用

页码：2089 / 2092

页数：4

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