HIV type 1 isolates from 200 untreated individuals in Ho Chi Minh City (Vietnam):: ANRS 1257 study.: Large predominance of CRF01_AE and presence of major resistance mutations to antiretroviral drugs

被引：40

作者：

Nguyen, THL

Recordon-Pinson, P

Pham, VH

Nguyen, TVU

Truong, TXL

Huynh, TT

Garrigue, I

Schrive, MH

Pellegrini, I

Lafon, ME

Aboulker, JP

Barré-Sinoussi, F

Fleury, HJ

机构：

[1] Inst Pasteur, Paris, France

[2] INSERM, SC10, Paris, France

[3] Universite, Ho Chi Minh Ville, Vietnam

[4] Inst Pasteur, Ho Chi Minh Ville, Vietnam

[5] Univ Bordeaux 2, Virol Lab, F-33076 Bordeaux, France

[6] Ctr Med Prevent, Ho Chi Minh Ville, Vietnam

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2003年 / 19卷 / 10期

关键词：

D O I：

10.1089/088922203322493111

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

HIV-1 isolates from 200 untreated patients recruited in 2001 and 2002 in the south part of Vietnam and particularly in Ho Chi Minh City were sequenced in the RT, protease, and env genes. Out of 200 isolates 198 belonged to CRF01_ AE while only one subtype B and one intersubtype (B-CRF01_AE) recombinant could be observed. Of the isolates 6.5% had major resistance mutations to antiretroviral drugs.

引用

页码：925 / 928

页数：4

共 10 条

[1] Sequence analysis of env C2/V3, gag p17/p24, and pol protease regions of 25 HIV type 1 isolates from Ho Chi Minh City, Vietnam [J].

Caumont, A ;

Lan, NTH ;

Uyen, NTV ;

Hung, PV ;

Schvoerer, E ;

Urriza, MSG ;

Roques, P ;

Schrive, MH ;

Lien, TTX ;

Lafon, ME ;

Dormont, D ;

Barre-Sinousi, F ;

Fleury, HJA .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2001, 17 (13) :1285-1291

[2] HIV type 1 diversity in France, 1999-2001: Molecular characterization of non-B HIV type 1 subtypes and potential impact on susceptibility to antiretroviral drugs [J].

Fleury, H ;

Recordon-Pinson, P ;

Caumont, A ;

Faure, M ;

Roques, P ;

Plantier, JC ;

Couturier, E ;

Dormont, D ;

Masquelier, B ;

Simon, F .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2003, 19 (01) :41-47

[3] Closely related HIV-1CRFO1_AE variant among injecting drug users in northern Vietnam: Evidence of HIV spread across the Vietnam-China border [J].

Kato, K ;

Kusagawa, S ;

Motomura, K ;

Yang, RG ;

Shiino, T ;

Nohtomi, K ;

Sato, H ;

Shibamura, K ;

Hien, NT ;

Chi, PK ;

Thang, PH ;

Thanh, DG ;

Quoc, NC ;

Thang, BD ;

Long, HT ;

Nagai, Y ;

Takebe, Y .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2001, 17 (02) :113-123

[4] Further characterization of HIV-1 isolates from Ho Chi Minh City, Vietnam [J].

Lan, NTH ;

Masquelier, B ;

Van Hung, P ;

Uyen, NTV ;

Lafon, ME ;

Lien, TTX ;

Chi, NH ;

Sinoussi, FB ;

Fleury, HJA .

JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 1999, 20 (01) :93-95

[5] ZIDOVUDINE-RESISTANT HUMAN-IMMUNODEFICIENCY-VIRUS SELECTED BY PASSAGE IN CELL-CULTURE [J].

LARDER, BA ;

COATES, KE ;

KEMP, SD .

JOURNAL OF VIROLOGY, 1991, 65 (10) :5232-5236

[6] HIV type 1 Thai subtype E is predominant in south Vietnam [J].

Menu, E ;

Lien, TTX ;

Lafon, ME ;

Lan, NTH ;

MullerTrutwin, MC ;

Thuy, NT ;

Deslandres, A ;

Chaouat, G ;

Trung, DQ ;

Khiem, HB ;

Fleury, HJA ;

BarreSinoussi, F .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1996, 12 (07) :629-633

[7] Comparison of capillary electrophoresis sequencing with the new CEQ 2000 DNA Analysis System to conventional gel based systems for HIV drug resistance analysis [J].

Merel, P ;

Pellegrin, I ;

Garrigue, I ;

Caumont, A ;

Schrive, MH ;

Birac, V ;

Bonot, P ;

Fleury, H .

JOURNAL OF VIROLOGICAL METHODS, 2001, 98 (01) :9-16

[8]

Nerurkar VR, 1997, CELL MOL BIOL, V43, P959

[9] HIV type 1 subtype E in commercial sex workers and injection drug users in southern Vietnam [J].

Nerurkar, VR ;

Nguyen, HT ;

Dashwood, WM ;

Hoffmann, PR ;

Yin, CQ ;

Morens, DM ;

Kaplan, AH ;

Detels, R ;

Yanagihara, R .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1996, 12 (09) :841-843

[10] Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: Evidence of many minor drug resistance mutations in treatment-naive patients [J].

Vergne, L ;

Peeters, M ;

Mpoudi-Ngole, E ;

Bourgeois, A ;

Liegeois, F ;

Toure-Kane, C ;

Mboup, S ;

Mulanga-Kabeya, C ;

Saman, E ;

Jourdan, J ;

Reynes, J ;

Delaporte, E .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (11) :3919-3925

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