Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT

被引:51
作者
Hu, Hui
Djuretic, Ivana
Sundrud, Mark S.
Rao, Anjana [1 ]
机构
[1] Harvard Univ, Sch Med, CBR Inst Biomed Res, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
关键词
D O I
10.1016/j.it.2007.06.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A general theme in gene regulation is that transcription factors never function alone. Recent studies have emphasized this concept for regulatory T cells, a unique lineage of CD4(+) T cells that exert active immune suppression and are essential to maintaining self-tolerance.
引用
收藏
页码:329 / 332
页数:4
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