Cardiovascular actions of magnesium

被引：41

作者：

Agus, MSD

Agus, ZS

机构：

[1] MassGen Hosp Children, Div Pediat Crit Care Med, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Childrens Hosp, Div Endocrinol, Boston, MA USA

[3] Univ Penn, Sch Med, Dept Med, Renal Electrolyte & Hypertens Div, Philadelphia, PA 19104 USA

来源：

CRITICAL CARE CLINICS | 2001年 / 17卷 / 01期

关键词：

D O I：

10.1016/S0749-0704(05)70158-5

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Extracellular and intracellular magnesium modulates calcium and potassium channels in the cardiac myocyte. Changes in concentration ha iie marked effects upon the action potential duration and can have important consequences in magnesium depletion syndromes and during cardiac ischemia. A number of clinical studies have suggested that hypomagnesemia and magnesium depletion are associated with ventricular arrhythmias, possibly reflecting the effects of magnesium upon ion channels.

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页码：175 / +

页数：13

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