Antipsychotics in the treatment of autism

被引：129

作者：

Posey, David J. ^{[1
]}

Stigler, Kimberly A. ^{[1
]}

Erickson, Craig A. ^{[1
]}

McDougle, Christopher J. ^{[1
]}

机构：

[1] Indiana Univ, Sch Med, Dept Psychiat, Riley Hosp,Christian Sarkine Austism Treatment Ct, Indianapolis, IN 46202 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2008年 / 118卷 / 01期

关键词：

D O I：

10.1172/JCI32483

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Atypical antipsychotics have become indispensable in the treatment of a variety of symptoms in autism. They are frequently used to treat irritability and associated behaviors including aggression and self injury. They may also be efficacious for hyperactivity and stereotyped behavior. This review presents the rationale for the use of this drug class in autism and reviews the most important studies published on this topic to date. Significant adverse effects, including weight gain and the possibility of tardive dyskinesia, are reviewed. Future research directions are discussed.

引用

页码：6 / 14

页数：9

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