Antibiotics in sepsis: Timing, appropriateness, and (of course) timely recognition of appropriateness

被引：14

作者：

Mikkelsen, Mark E. ^{[1
]}

Gaieski, David F. ^{[2
]}

机构：

[1] Univ Penn, Sch Med, Dept Med, Pulm Allergy & Crit Care Div, Philadelphia, PA 19104 USA

[2] Univ Penn, Sch Med, Dept Emergency Med, Philadelphia, PA 19104 USA

来源：

CRITICAL CARE MEDICINE | 2011年 / 39卷 / 09期

关键词：

appropriate antibiotics; emergency medicine; goal-directed resuscitation; septic shock; severe sepsis; time to antibiotics; GOAL-DIRECTED THERAPY; UNITED-STATES; SEPTIC SHOCK; SURVIVAL; EPIDEMIOLOGY; INITIATION; LACTATE;

D O I：

10.1097/CCM.0b013e3182226ffa

中图分类号：

R4 [临床医学];

学科分类号：

100218 [急诊医学];

摘要：

引用

页码：2184 / 2186

页数：3

共 12 条

[1]

[Anonymous], CRIT CARE MED

[2]

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 [J].

Dellinger, R. Phillip ;

Levy, Mitchell M. ;

Carlet, Jean M. ;

Bion, Julian ;

Parker, Margaret M. ;

Jaeschke, Roman ;

Reinhart, Konrad ;

Angus, Derek C. ;

Brun-Buisson, Christian ;

Beale, Richard ;

Calandra, Thierty ;

Dhainaut, Jean-Francois ;

Gerlach, Herwig ;

Harvey, Maurene ;

Marini, John J. ;

Marshall, John ;

Ranieri, Marco ;

Ramsay, Graham ;

Sevransky, Jonathan ;

Thompson, B. Taylor ;

Townsend, Sean ;

Vender, Jeffrey S. ;

Zimmerman, Janice L. ;

Vincent, Jean-Louis .

CRITICAL CARE MEDICINE, 2008, 36 (01) :296-327

[3]

Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department [J].

Gaieski, David F. ;

Mikkelsen, Mark E. ;

Band, Roger A. ;

Pines, Jesse M. ;

Massone, Richard ;

Furia, Frances F. ;

Shofer, Frances S. ;

Goyal, Munish .

CRITICAL CARE MEDICINE, 2010, 38 (04) :1045-1053

[4]

Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy A Randomized Clinical Trial [J].

Jones, Alan E. ;

Shapiro, Nathan I. ;

Trzeciak, Stephen ;

Arnold, Ryan C. ;

Claremont, Heather A. ;

Kline, Jeffrey A. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (08) :739-746

[5]

The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock:: Association with serum lactate and inflammatory cytokine levels [J].

Kumar, A ;

Haery, C ;

Paladugu, B ;

Kumar, A ;

Symeoneides, S ;

Taiberg, L ;

Osman, J ;

Trenholme, G ;

Opal, SM ;

Goldfarb, R ;

Parrillo, JE .

JOURNAL OF INFECTIOUS DISEASES, 2006, 193 (02) :251-258

[6]

Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock [J].

Kumar, Anand ;

Ellis, Paul ;

Arabi, Yaseen ;

Roberts, Dan ;

Light, Bruce ;

Parrillo, Joseph E. ;

Dodek, Peter ;

Wood, Gordon ;

Kumar, Aseem ;

Simon, David ;

Peters, Cheryl ;

Ahsan, Muhammad ;

Chateau, Dan .

CHEST, 2009, 136 (05) :1237-1248

[7]

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock [J].

Kumar, Arland ;

Roberts, Daniel ;

Wood, Kenneth E. ;

Light, Bruce ;

Parrillo, Joseph E. ;

Sharma, Satendra ;

Suppes, Robert ;

Feinstein, Daniel ;

Zanotti, Sergio ;

Taiberg, Leo ;

Gurka, David ;

Kumar, Aseem ;

Cheang, Mary .

CRITICAL CARE MEDICINE, 2006, 34 (06) :1589-1596

[8]

Adjustments for center in multicenter studies: An overview [J].

Localio, AR ;

Berlin, JA ;

Ten Have, TR ;

Kimmel, SE .

ANNALS OF INTERNAL MEDICINE, 2001, 135 (02) :112-123

[9]

The epidemiology of sepsis in the United States from 1979 through 2000 [J].

Martin, GS ;

Mannino, DM ;

Eaton, S ;

Moss, M .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (16) :1546-1554

[10]

Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol [J].

Puskarich, Michael A. ;

Trzeciak, Stephen ;

Shapiro, Nathan I. ;

Arnold, Ryan C. ;

Horton, James M. ;

Studnek, Jonathan R. ;

Kline, Jeffrey A. ;

Jones, Alan E. .

CRITICAL CARE MEDICINE, 2011, 39 (09) :2066-2071

← 1 2 →