RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma

被引:69
作者
Sharma, MK
Zehnbauer, BA
Watson, MA
Gutmann, DH
机构
[1] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA
[3] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
关键词
D O I
10.1212/01.wnl.0000180409.78098.d7
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:1335 / 1336
页数:2
相关论文
共 7 条
[1]  
Dasgupta B, 2005, CANCER RES, V65, P236
[2]   Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene [J].
Gressani, KM ;
Rollins, LA ;
Leone-Kabler, S ;
Cline, JM ;
Miller, MS .
CARCINOGENESIS, 1998, 19 (06) :1045-1052
[3]   Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas [J].
Gutmann, DH ;
Donahoe, J ;
Brown, T ;
James, CD ;
Perry, A .
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2000, 26 (04) :361-367
[4]   Cancer-related gene expression profiles in NF1-associated pilocytic astrocytomas [J].
Li, J ;
Perry, A ;
James, CD ;
Gutmann, DH .
NEUROLOGY, 2001, 56 (07) :885-890
[5]   Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis [J].
Loh, ML ;
Vattikuti, S ;
Schubbert, S ;
Reynolds, MG ;
Carlson, E ;
Lieuw, KH ;
Cheng, JW ;
Lee, CM ;
Stokoe, D ;
Bonifas, JM ;
Curtiss, NP ;
Gotlib, J ;
Meshinchi, S ;
Le Beau, MM ;
Emanuel, PD ;
Shannon, KM .
BLOOD, 2004, 103 (06) :2325-2331
[6]   Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia [J].
Tartaglia, M ;
Niemeyer, CM ;
Fragale, A ;
Song, XL ;
Buechner, J ;
Jung, A ;
Hählen, K ;
Hasle, H ;
Licht, JD ;
Gelb, BD .
NATURE GENETICS, 2003, 34 (02) :148-150
[7]   Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas [J].
Wimmer, K ;
Eckart, M ;
Meyer-Puttlitz, B ;
Fonatsch, C ;
Pietsch, T .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2002, 61 (10) :896-902