Caspofungin associated with liposomal amphotericin B or voriconazole for treatment of refractory fungal pneumonia in children with acute leukaemia or undergoing allogeneic bone marrow transplant

被引：22

作者：

Castagnola, E

Machetti, M

Cappelli, B

Molinari, AC

Morreale, G

Dodero, P

Toma, P

Faraci, M

机构：

[1] G Gaslini Childrens Hosp, Infect Dis Unit, I-16147 Genoa, Italy

[2] Univ Genoa, Genoa, Italy

[3] Natl Inst Canc Res, Genoa, Italy

[4] G Gaslini Childrens Hosp, Unit Bone Marrow Transplant, Genoa, Italy

[5] G Gaslini Childrens Hosp, Unit Haematol, Genoa, Italy

[6] G Gaslini Childrens Hosp, Surg Unit, Genoa, Italy

[7] G Gaslini Childrens Hosp, Serv Radiol, Genoa, Italy

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2004年 / 10卷 / 03期

关键词：

amphotericin B; bone marrow transplant; caspofungin; fungal pneumonia; leukaemia; voriconazole;

D O I：

10.1111/j.1198-743X.2004.00837.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Caspofungin, in association with other antifungal drugs, was administered as rescue therapy in two cases of documented and one case of possible invasive fungal infection in children with acute leukaemia or undergoing allogeneic bone marrow transplant. The combined therapy was well-tolerated and seemed to be effective in all three patients. A combination antifungal therapy including caspofungin could represent an effective therapy for children with invasive mycoses refractory to single-agent antifungal therapy.

引用

页码：255 / 257

页数：3

共 8 条

[1] Refractory aspergillus pneumonia in patients with acute leukemia - Successful therapy with combination caspofungin and liposomal amphotericin [J].