A Better TRAIL Variant for Tumor Cell-Specific Targeting? - Letter

被引：3

作者：

Bremer, Edwin ^{[1
]}

Helfrich, Wijnand ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Surg, Surg Res Lab, NL-9713 AV Groningen, Netherlands

来源：

MOLECULAR CANCER THERAPEUTICS | 2010年 / 9卷 / 10期

关键词：

FUSION PROTEIN; APOPTOSIS; INDUCTION; SUPERIOR;

D O I：

10.1158/1535-7163.MCT-10-0621

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

引用

页码：2853 / 2853

页数：1

共 5 条

[1]

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2 [J].

Bremer, E ;

Kuulen, J ;

Samplonius, D ;

Walczak, H ;

De Leu, L ;

Helfrich, W .

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[2]

Targeted delivery of a designed sTRAIL mutant results in superior apoptotic activity towards EGFR-positive tumor cells [J].

Bremer, Edwin ;

de Bruyn, Marco ;

Samplonius, Douwe F. ;

Bijma, Theo ;

ten Cate, Bram ;

de Leij, Lou F. M. H. ;

Helfrich, Wijnand .

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[3]

A Genetically Encoded Multifunctional TRAIL Trimer Facilitates Cell-Specific Targeting and Tumor Cell Killing [J].

Spitzer, Dirk ;

McDunn, Jonathan E. ;

Plambeck-Suess, Stacey ;

Goedegebuure, Peter S. ;

Hotchkiss, Richard S. ;

Hawkins, William G. .

MOLECULAR CANCER THERAPEUTICS, 2010, 9 (07) :2142-2151

[4]

Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein [J].

Stieglmaier, Julia ;

Bremer, Edwin ;

Kellner, Christian ;

Liebig, Tanja M. ;

ten Cate, Bram ;

Peipp, Matthias ;

Schulze-Koops, Hendrik ;

Pfeiffer, Matthias ;

Buehring, Hans-Joerg ;

Greil, Johann ;

Oduncu, Fuat ;

Emmerich, Bertold ;

Fey, Georg H. ;

Helfrich, Wijnand .

CANCER IMMUNOLOGY IMMUNOTHERAPY, 2008, 57 (02) :233-246

[5]

A novel AML-selective TRAIL fusion protein that is superior to Gemtuzumab Ozogamicin in terms of in vitro selectivity, activity and stability [J].

ten Cate, B. ;

Bremer, E. ;

de Bruyn, M. ;

Bijma, T. ;

Samplonius, D. ;

Schwemmlein, M. ;

Huls, G. ;

Fey, G. ;

Helfrich, W. .

LEUKEMIA, 2009, 23 (08) :1389-1397

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