Left ventricular mass and function in young obese women

被引:18
作者
Crisostomo, LL
Araújo, LMB
Câmara, E
Carvalho, C
Silva, FA
Vieira, M
Mendes, CMC
Rabelo, A
机构
[1] Fdn Bahiana Cardiol Salvador, Salvador, BA, Brazil
[2] Univ Fed Bahia, Div Endocrinol, Salvador, BA, Brazil
[3] Univ Fed Bahia, Sch Med, Salvador, BA, Brazil
关键词
left ventricular mass; ventricular function; ventricular hypertrophy; echocardiography; obesity;
D O I
10.1038/sj.ijo.0801460
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE: Obesity is associated with a high mortality rate due to cardiovascular disease. Left ventricular (LV) hypertrophy has been described in relation to obesity. The aim of this study was to evaluate echocardiographically the LV mass and function in young obese women as compared to lean women with similar characteristics. DESIGN: Prospective study. SUBJECTS: Eighty-two young women (less than or equal to 40 y), with obesity degree varying from I to III (BMI from 30 to 50 kg/m(2)) were compared to eighty young lean women. All of them were normotensive, none had cardiovascular complaints or any previous history of pulmonary disease, and none were taking any medication. The LV mass was calculated by the Devereux and Reichek formula. RESULTS: The LV mass was strongly increased in all obese groups (P < 0.00003 to 0.000005) compared to lean subjects. LV mass adjusted indexes for height, BMI or volume were also increased compared to lean subjects and when adjusted for weight it was decreased. However when comparing LV mass/body surface area index this difference was not statistically significant. The linear regression analysis showed a strong association between the degree of obesity and LV mass, (r = 0.52, P < 0.001). Systolic and diastolic function in obese patients were similar to lean subjects, except for a lower E/A ratio in the obese group (P = 0.005). CONCLUSION: In asymptomatic young obese women, there are some echocardiographic findings suggesting early cardiac involvement that seems to be related to the degree of obesity.
引用
收藏
页码:233 / 238
页数:6
相关论文
共 31 条
  • [1] FACTORS INFLUENCING LEFT-VENTRICULAR SYSTOLIC FUNCTION IN NONHYPERTENSIVE MORBIDLY OBESE PATIENTS, AND EFFECT OF WEIGHT-LOSS INDUCED BY GASTROPLASTY
    ALPERT, MA
    TERRY, BE
    LAMBERT, CR
    KELLY, DL
    PANAYIOTOU, H
    MUKERJI, V
    MASSEY, CV
    COHEN, MV
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1993, 71 (08) : 733 - 737
  • [2] Cardiac morphology and left ventricular function in normotensive morbidly obese patients with and without congestive heart failure, and effect of weight loss
    Alpert, MA
    Terry, BE
    Mulekar, M
    Cohen, MV
    Massey, CV
    Fan, TM
    Panayiotou, H
    Mukerji, V
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1997, 80 (06) : 736 - 740
  • [3] ALPERT MA, 1995, INT J OBESITY, V19, P550
  • [4] INFLUENCE OF LEFT-VENTRICULAR MASS ON LEFT-VENTRICULAR DIASTOLIC FILLING IN NORMOTENSIVE MORBID-OBESITY
    ALPERT, MA
    LAMBERT, CR
    TERRY, BE
    COHEN, MV
    MUKERJI, V
    MASSEY, CV
    HASHIMI, MW
    PANAYIOTOU, H
    [J]. AMERICAN HEART JOURNAL, 1995, 130 (05) : 1068 - 1073
  • [5] EFFECT OF WEIGHT-LOSS ON CARDIAC CHAMBER SIZE, WALL THICKNESS AND LEFT-VENTRICULAR FUNCTION IN MORBID-OBESITY
    ALPERT, MA
    TERRY, BE
    KELLY, DL
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1985, 55 (06) : 783 - 786
  • [6] RELATION OF DURATION OF MORBID-OBESITY TO LEFT-VENTRICULAR MASS, SYSTOLIC FUNCTION, AND DIASTOLIC FILLING, AND EFFECT OF WEIGHT-LOSS
    ALPERT, MA
    LAMBERT, CR
    PANAYIOTOU, H
    TERRY, BE
    COHEN, MV
    MASSEY, CV
    HASHIMI, MW
    MUKERJI, V
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1995, 76 (16) : 1194 - +
  • [7] CARDIAC PATHOLOGY OF CHRONIC EXOGENOUS OBESITY
    AMAD, KH
    BRENNAN, JC
    ALEXANDER, JK
    [J]. CIRCULATION, 1965, 32 (05) : 740 - +
  • [8] Relations of left ventricular mass to fat-free and adipose body mass - The strong heart study
    Bella, JN
    Devereux, RB
    Roman, MJ
    O'Grady, MJ
    Welty, TK
    Lee, ET
    Fabsitz, RR
    Howard, BV
    [J]. CIRCULATION, 1998, 98 (23) : 2538 - 2544
  • [9] VALUE OF ECHOCARDIOGRAPHIC MEASUREMENT OF LEFT-VENTRICULAR MASS IN PREDICTING CARDIOVASCULAR MORBID EVENTS IN HYPERTENSIVE MEN
    CASALE, PN
    DEVEREUX, RB
    MILNER, M
    ZULLO, G
    HARSHFIELD, GA
    PICKERING, TG
    LARAGH, JH
    [J]. ANNALS OF INTERNAL MEDICINE, 1986, 105 (02) : 173 - 178
  • [10] ABNORMAL LEFT-VENTRICULAR DIASTOLIC FILLING IN ECCENTRIC LEFT-VENTRICULAR HYPERTROPHY OF OBESITY
    CHAKKO, S
    MAYOR, M
    ALLISON, MD
    KESSLER, KM
    MATERSON, BJ
    MYERBURG, RJ
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1991, 68 (01) : 95 - 98