Photoreactions of hypocrellin B with thiol compounds

被引：45

作者：

He, YY ^{[1
]}

An, JY ^{[1
]}

Zou, W ^{[1
]}

Jiang, LJ ^{[1
]}

机构：

[1] Acad Sinica, Inst Photog Chem, Beijing 100101, Peoples R China

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 1998年 / 44卷 / 01期

关键词：

hypocrellin B; thiol compounds; photoreduction; photothiylation; nucleophilic anionic addition;

D O I：

10.1016/S1011-1344(98)00116-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The photoreactions of hypocrellin B (HB) with thiol compounds (RSH) in ethanol buffer solutions have been investigated by electron spin resonance (ESR), alpha-phenyl-N-tert-butyl nitrone (PBN) spin trapping and quenching experiments. The mechanism of photothiylation of HE is proposed to involve a nucleophilic anion (RS-) addition of Michael type at the 5 or/and 8 positions followed by oxidation. The effects of oxygen and pH value have been studied. The photoreaction and thermal reaction have been compared. (C) 1998 Elsevier Science S.A. All rights reserved.

引用

页码：45 / 52

页数：8

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