In preterm neonates, is the risk of developing bronchopulmonary dysplasia influenced by the failure to protect total parenteral nutrition from exposure to ambient light?

被引：38

作者：

Chessex, Philippe

Harrison, Adele

Khashu, Minesh

Lavoie, Jean-Claude

机构：

[1] Womens & Childrens Hosp, Div Neonatol, Vancouver, BC V6H 3V4, Canada

[2] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada

[3] Univ Montreal, Dept Pediat, Hop Sainte Justine, Montreal, PQ H3C 3J7, Canada

来源：

JOURNAL OF PEDIATRICS | 2007年 / 151卷 / 02期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1016/j.jpeds.2007.04.029

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Light-exposed total parenteral nutrition (TPN) generates peroxides that contribute to an oxidant load. Shielding TPN from light protects against lung remodelling. In preterm infants, photoprotection of TPN is associated with a 30% reduction in bronchopulmonary dysplasia, in a post-hoe analysis. This analysis provides justification for a randomized controlled trial.

引用

收藏

页码：213 / 214

页数：2

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