The prevalence of lower urinary tract symptoms in men and women in four centres. The UrEpik study

被引:219
作者
Boyle, P
Robertson, C
Mazzetta, C
Keech, M
Fourcade, R
Kiemeney, L
Lee, C
机构
[1] European Inst Oncol, Div Epidemiol & Biostat, I-20141 Milan, Italy
[2] GlaxoSmithKline, Global Hlth Outcomes, Middlesex, England
[3] Univ Birmingham, Sch Med, Dept Primary Care & Gen Practice, Birmingham, W Midlands, England
[4] CHU Auxerre, Serv Urol, Auxerre, France
[5] Univ Med Ctr Nijmegen, Dept Urol, Nijmegen, Netherlands
[6] Seoul Natl Univ Hosp, Dept Urol, Seoul 110744, South Korea
关键词
LUTS; prevalence; cultural; age; gender;
D O I
10.1046/j.1464-410X.2003.04369.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE To evaluate the epidemiology of lower urinary tract symptoms (LUTS) among men and women, as there are significant unanswered questions about the prevalence and impact of LUTS in different populations. SUBJECTS AND METHODS A population-based, cross-sectional survey was completed in Boxmeer ( the Netherlands), Auxerre ( France), Birmingham (UK) and Seoul ( Republic of Korea), using culturally and linguistically validated versions of the International Prostate Symptom Score (IPSS). The aim was to estimate the distribution of symptoms of LUTS in men and women. Stratified random samples of men aged 40 79 years in each community were collected. Postal questionnaires were used in Europe and direct interviews in Korea. RESULTS In all, 4979 index men and 3790 women were recruited, with age-adjusted response rates among men of 72% in Boxmeer, 28% in Auxerre, 60% in Birmingham and 68% in Seoul. The percentages of men and women with an IPSS of 8 - 35, indicating moderate to severe symptoms, were, respectively, 20.7 and 18.0 (Boxmeer); 19.2 and 12.6 ( Auxerre); 25.1 and 23.7 ( Birmingham); 16.2 and 19.9 ( Seoul). Among women the relationship between symptoms and age was not as strong as in men. The percentages of men and women with moderate to severe symptoms were by age group, respectively, 10.6, 15.5 ( 40 - 49); 19.0, 18.2 ( 50 - 59); 30.5, 23.8 ( 60 - 69); 40.4, 28.7 ( 70 - 79). Among those aged 40 - 49 the main differences between men and women were in the questions about frequency of urination during the day and holding back urine. Among the older groups men reported more symptoms on all questions apart from urination at night and difficulty in holding back urine, both of which were equally prevalent among men and women. CONCLUSIONS The overall prevalence of LUTS was high and showed no marked cultural variation. Prevalence increased with age, with severe LUTS commoner in older men. Women reported similar levels of the symptoms traditionally associated with LUTS in men. In each age group there were no major cultural differences in the frequency of LUTS. There were differences with age between men and women; younger men had a lower prevalence of LUTS than younger women but older men a much higher prevalence than older women. These findings emphasize that the IPSS should be confined to within-patient comparisons and not used as a diagnostic tool. The IPSS performs very similarly regardless of gender.
引用
收藏
页码:409 / 414
页数:6
相关论文
共 28 条
[1]   THE AMERICAN-UROLOGICAL-ASSOCIATION SYMPTOM INDEX FOR BENIGN PROSTATIC HYPERPLASIA [J].
BARRY, MJ ;
FOWLER, FJ ;
OLEARY, MP ;
BRUSKEWITZ, RC ;
HOLTGREWE, HL ;
MEBUST, WK ;
COCKETT, ATK ;
BLAIVAS, JG ;
WEIN, AJ .
JOURNAL OF UROLOGY, 1992, 148 (05) :1549-1557
[2]   Strong effects of definition and nonresponse bias on prevalence rates of clinical benign prostatic hyperplasia: the Krimpen study of male urogenital tract problems and general health status [J].
Blanker, MH ;
Groeneveld, FPMJ ;
Prins, A ;
Bernsen, RMD ;
Bohnen, AM ;
Bosch, JLHR .
BJU INTERNATIONAL, 2000, 85 (06) :665-671
[3]  
BOYLE P, 1998, J EPIDEMIOL BIOSTAT, V3, P179
[4]   Prevalence of benign prostatic hyperplasia in Spanish men 40 years old or older [J].
Chicharro-Molero, JA ;
Burgos-Rodriguez, R ;
Sanchez-Cruz, JJ ;
Del Rosal-Samaniego, JM ;
Rodero-Carcia, P ;
Rodriguez-Vallejo, JM .
JOURNAL OF UROLOGY, 1998, 159 (03) :878-882
[5]  
Choi J, 2002, EUR UROL, V42, P7, DOI 10.1016/S0302-2838(02)00222-1
[6]   Prostate disease: Epidemiology, natural history and demographic shifts [J].
Garraway, WM ;
Alexander, FE .
BRITISH JOURNAL OF UROLOGY, 1997, 79 :3-8
[7]   Health-related quality of life associated with lower urinary tract symptoms in four countries [J].
Girman, CJ ;
Jacobsen, SJ ;
Tsukamoto, T ;
Richard, F ;
Garraway, WM ;
Sagnier, PP ;
Guess, HA ;
Rhodes, T ;
Boyle, P ;
Lieber, MM .
UROLOGY, 1998, 51 (03) :428-436
[8]  
Girman CJ, 1998, BRIT J UROL, V82, P34
[9]   The prevalence of lower urinary tract symptoms in Austrian males and associations with sociodemographic variables [J].
Haidinger, G ;
Madersbacher, S ;
Waldhoer, T ;
Lunglmayr, G ;
Vutuc, C .
EUROPEAN JOURNAL OF EPIDEMIOLOGY, 1999, 15 (08) :717-722
[10]   Risk factors for lower urinary tract symptoms in elderly men [J].
Haidinger, G ;
Temml, C ;
Schatzl, G ;
Brössner, C ;
Roehlich, M ;
Schmidbauer, CP ;
Madersbacher, S .
EUROPEAN UROLOGY, 2000, 37 (04) :413-420