Depression and Cognition in the Elderly

被引：118

作者：

Wang, Sophia ^{[1
,2
]}

Blazer, Dan G. ^{[1
,3
]}

机构：

[1] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC 27710 USA

[2] Durham Vet Affairs Med Ctr, Durham, NC 27705 USA

[3] Duke Univ, Med Ctr, Ctr Study Aging, Durham, NC 27710 USA

来源：

ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 11 | 2015年 / 11卷

关键词：

mild cognitive impairment; neurocognitive disorder; major depressive disorder; neuropsychological testing; neuroimaging; psychotherapy; antidepressants; brain stimulation therapies; LATE-LIFE DEPRESSION; PROBLEM-SOLVING THERAPY; TRANSCRANIAL MAGNETIC STIMULATION; OBSTRUCTIVE PULMONARY-DISEASE; CEREBROVASCULAR RISK-FACTORS; QUALITY-OF-LIFE; OLDER-ADULTS; DOUBLE-BLIND; EXECUTIVE DYSFUNCTION; GERIATRIC DEPRESSION;

D O I：

10.1146/annurev-clinpsy-032814-112828

中图分类号：

B849 [应用心理学];

学科分类号：

040203 [应用心理学];

摘要：

This review provides an overview of the relationship between depression and cognition in the elderly, with an emphasis on psychotherapies and nonpharmacologic approaches. We first review the clinical presentation of late-life depression and comorbid cognitive impairment, as well as the epidemiology and risk factors for cognitive impairment in late-life depression and the temporal relationship between depression and cognitive impairment. Next, we discuss the salient topic of elderly suicide and cognitive impairment. We then touch briefly on the neuropsychological deficits, biomarkers, and neuroimaging findings in late-life depression with comorbid cognitive impairment. We then focus most of this review on psychotherapies and nontraditional treatments for late-life depression with comorbid cognitive impairment and examine what evidence, if any, exists of the cognitive and functional benefits of these treatments. Finally, we examine the cognitive effects of pharmacologic treatments and brain stimulation therapies.

引用

页码：331 / 360

页数：30

共 144 条

[1]

Depression and Cognitive Function in Maintenance Hemodialysis Patients [J].