The synthesis and transformations of substituted 2-hydroxy-3-dimethylaminopropenoates. The preparation of condensed 3-hydroxypyran-2-ones

被引：43

作者：

Smodis, J ^{[1
]}

Stanovnik, B ^{[1
]}

机构：

[1] Univ Ljubljana, Dept Chem & Chem Technol, Ljubljana 1001, Slovenia

来源：

TETRAHEDRON | 1998年 / 54卷 / 33期

关键词：

D O I：

10.1016/S0040-4020(98)00534-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient synthesis of substituted 2-hydroxy-3-dimethylaminopropenoates is reported. They react with cyclic 1,3-diketones, with aromatic and heteroaromatic hydroxy compounds to afford the corresponding 3-substituted hydroxytetrahydro-2H-1-benzopyran-2-ones, benzo- and naphthopyran-2-ones and azolo- and azinopyran-2-ones, respectively. Catalytic debenzylation of 3-benzyloxy substituted fused pyran-2-ones gives free 3-hydroxy derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9799 / 9810

页数：12

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