Functional MRI activation of individual interictal epileptiform spikes

被引:54
作者
Krakow, K [1 ]
Messina, D
Lemieux, L
Duncan, JS
Fish, DR
机构
[1] UCL, Neurol Inst, Dept Clin Neurol, Epilepsy Res Grp, London, England
[2] Natl Soc Epilepsy, Gerrards Cross, Bucks, England
[3] Univ Frankfurt, Dept Neurol, D-6000 Frankfurt, Germany
[4] Univ Catanzaro, Sch Med, Neurol Inst, Catanzaro, Italy
关键词
D O I
10.1006/nimg.2000.0708
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We used spike-triggered functional MRI in a patient with localization-related epilepsy to determine whether individual (as opposed to averaged) focal interictal epileptiform discharges (spikes) were associated with hemodynamic changes detectable with blood oxygen level-dependent functional MRI (fMRI). It was found that 15 of 43 spikes (34.9%) were associated with significant focal fMRI activation. Single event-related fMRI of interictal spikes is feasible in selected patients, giving complementary information to that provided by averaged fMRI data. (C) 2001 Academic Press.
引用
收藏
页码:502 / 505
页数:4
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