Treatment of intracranial ependymoma by surgery alone

被引:78
作者
Hukin, J
Epstein, F
Lefton, D
Allen, J
机构
[1] Beth Israel Deaconess Med Ctr, N Div, Inst Neurol & Neurosurg, Dept Neurol, New York, NY 10128 USA
[2] Beth Israel Deaconess Med Ctr, Dept Radiol, New York, NY 10128 USA
[3] Beth Israel Deaconess Med Ctr, Dept Neurosurg, New York, NY 10128 USA
关键词
intracranial ependymoma; gross total resection alone;
D O I
10.1159/000028683
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: This study aimed to determine the safety of deferring radiotherapy in pediatric intracranial ependymoma following a radiographically confirmed gross total resection in patients with localized disease. Methods: Children over age 3 were recruited prospectively from 1990 to 1997, following a surgical impression and radiologic confirmation of a gross total resection of an intracranial ependymoma. Results: 10/32 cases of intracranial ependymomas were both eligible and gave consent. 7 remain free of disease without further intervention. 3 recurred, 2 were salvaged with surgery and radiotherapy, none died. Conclusions: Deferral of radiotherapy following gross total resection alone is a safe option in supratentorial ependymomas. The pattern of recurrence is usually local and patients may be salvaged with additional surgery with or without radiotherapy.
引用
收藏
页码:40 / 45
页数:6
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