Skin occlusion and irritant and allergic contact dermatitis: an overview

被引：71

作者：

Zhai, HB ^{[1
]}

Maibach, HI ^{[1
]}

机构：

[1] Univ Calif San Francisco, Sch Med, Dept Dermatol, San Francisco, CA 94143 USA

来源：

CONTACT DERMATITIS | 2001年 / 44卷 / 04期

关键词：

enhancer; irritant contact dermatitis; occlusion; percutaneous absorption-penetration; stratum corneum; transdermal therapeutic systems; transepidermal water loss;

D O I：

10.1034/j.1600-0536.2001.044004201.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Occlusion, widely used to enhance percutaneous absorption of drugs, also increases penetration of other chemicals and antigens, and hence may exacerbate irritant and allergic contact dermatitis. This overview summarizes the adverse effects of occlusion.

引用

页码：201 / 206

页数：6

共 44 条

[1]

BAKER H, 1972, TXB DERMATOLOGY, P249

[2]

BERARDESCA E, 1988, Skin Pharmacology, V1, P207

[3] ADVERSE SKIN REACTIONS TO NICOTINE IN A TRANSDERMAL THERAPEUTIC SYSTEM [J].

BIRCHER, AJ ;

HOWALD, H ;

RUFLI, T .

CONTACT DERMATITIS, 1991, 25 (04) :230-236

[4]

BODDE HE, 1989, CRIT REV THER DRUG, V6, P87

[5]

Bucks D., 1999, Percutaneous absorption: drug-cosmetics-mechanisms-methodology, V3rd ed, P81

[6]

BUCKS D, 1991, IN VITRO PERCUTANEOU, P85

[7] BIOAVAILABILITY OF TOPICALLY ADMINISTERED STEROIDS - A MASS BALANCE TECHNIQUE [J].

BUCKS, DAW ;

MCMASTER, JR ;

MAIBACH, HI ;

GUY, RH .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1988, 91 (01) :29-33

[8]

Cleary G., 1993, TOPICAL DRUG BIOAVAI

[9]

CLEARY GW, 1993, SKIN PERMEATION FUND, P207

[10] Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption: Implication for seasonal exacerbations of inflammatory dermatoses [J].

Denda, M ;

Sato, J ;

Tsuchiya, T ;

Elias, PM ;

Feingold, KR .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1998, 111 (05) :873-878

← 1 2 3 4 5 →