Intramolecular 1,3-dipolar cycloadditions of norbornadiene-tethered nitrones

被引：36

作者：

Tranmer, GK ^{[1
]}

Tam, W ^{[1
]}

机构：

[1] Univ Guelph, Dept Chem & Biochem, Guelph Waterloo Ctr Grad Work Chem & Biochem, Guelph, ON N1G 2W1, Canada

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 15期

关键词：

D O I：

10.1021/jo015610b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient routes to the synthesis of norbornadiene-tethered nitrones have been developed, and their intramolecular 1,3-dipolar cycloadditions were studied. The cycloadditions occurred in moderate to good yields for a variety of substrates and were found to be highly regio- and stereoselective, giving single regio- and stereoisomers in most cases.

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页码：5113 / 5123

页数：11

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