Gas dynamic virtual nozzle for generation of microscopic droplet streams

被引:415
作者
DePonte, D. P. [1 ]
Weierstall, U. [1 ]
Schmidt, K. [1 ]
Warner, J. [1 ]
Starodub, D. [1 ]
Spence, J. C. H. [1 ]
Doak, R. B. [1 ]
机构
[1] Arizona State Univ, Dept Phys, Tempe, AZ 85287 USA
基金
美国国家科学基金会;
关键词
D O I
10.1088/0022-3727/41/19/195505
中图分类号
O59 [应用物理学];
学科分类号
摘要
As shown by Ganan-Calvo (1998 Phys. Rev. Lett. 80 285-8), a free liquid jet can be compressed in diameter through gas dynamic forces exerted by a coaxially co-flowing gas, obviating the need for a solid nozzle to form a microscopic liquid jet and thereby alleviating the clogging problems that plague conventional droplet sources of small diameter. We describe in this paper a novel form of droplet beam source based on this principle. The source is miniature, robust, dependable, easily fabricated, essentially immune to clogging and eminently suitable for delivery of microscopic liquid droplets, including hydrated biological samples, into vacuum for analysis using vacuum instrumentation. Monodisperse, single-file droplet streams are generated by triggering the device with a piezoelectric actuator.
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页数:7
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