Cell biology - Boa constrictor or rattlesnake?

被引：19

作者：

Kirchhausen, T

机构：

[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA

[2] Ctr Blood Res, Boston, MA 02115 USA

来源：

NATURE | 1999年 / 398卷 / 6727期

关键词：

D O I：

10.1038/18989

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

During endocytosis, dynamin forms a spiral collar around the neck of budding vesicles, which are then pinched off. The dynamin ring is thought to change shape, and constrict, in response to GTP hydrolysis. But a study of dynamin mutants that cannot hydrolyse GTP shows that this is not the case, and means that we need to rethink the previous model.

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页码：470 / 471

页数：2

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