Trans lipids: The free radical path

被引：117

作者：

Chatgilialoglu, C ^{[1
]}

Ferreri, C ^{[1
]}

机构：

[1] CNR, ISOF, I-40129 Bologna, Italy

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2005年 / 38卷 / 06期

关键词：

D O I：

10.1021/ar0400847

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Free radical-catalyzed cis-transisomerization of unsaturated lipids and its outcome in biomimetic conditions are reviewed. They provided indications for an endogenous origin of trans unsaturated fatty acids in humans by the attack of thiyl radicals. A multidisciplinary approach highlights the relevance of this topic. The role of cis lipid geometry and its maintenance in the biological environment is an emerging question, with future developments in the fields of lipidomics, biology, and medicine.

引用

收藏

页码：441 / 448

页数：8

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