Genotyping for polymorphisms in interferon-γ, interleukin-10, transforming growth factor-β1 and tumour necrosis factor-α genes:: a technical report

被引：222

作者：

Perrey, C ^{[1
]}

Pravica, V ^{[1
]}

Sinnott, PJ ^{[1
]}

Hutchinson, IV ^{[1
]}

机构：

[1] Univ Manchester, Sch Biol Sci, Immunol Res Grp, Manchester M13 9PT, Lancs, England

来源：

TRANSPLANT IMMUNOLOGY | 1998年 / 6卷 / 03期

关键词：

D O I：

10.1016/S0966-3274(98)80045-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Polymorphic Variants of cytokine genes are associated with acute and chronic transplant rejection. In this technical report, the methods currently used in our centre to genotype individuals for interferon-gamma, interleukin-10, transforming growth factor-beta 1 and tumour necrosis factor-alpha are described in detail. The DNA sequences of primers and probes, and conditions for polymerase chain reactions are given, and the allele and genotype frequencies in our control populations are summarized.

引用

页码：193 / 197

页数：5

共 13 条

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Turner, D
Grant, SCD
Yonan, N
Sheldon, S
Dyer, PA
Sinnott, PJ
Hutchinson, IV
[J]. TRANSPLANTATION, 1997, 64 (05) : 776 - 779

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