(S)-5,6-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenamine-L-(+)-mandelic acid (1/1): The absolute configuration of a precursor of the active stereoisomer of 5,6-ADTN, an important dopaminergic agonist

被引：1

作者：

Fantucci, M ^{[1
]}

Montanari, S ^{[1
]}

Santangelo, F ^{[1
]}

Ianelli, S ^{[1
]}

Nardelli, M ^{[1
]}

机构：

[1] UNIV PARMA,CNR,CTR STUDIO STRUTTURIST DIFFRATTOMETR,I-43100 PARMA,ITALY

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1996年 / 52卷

关键词：

D O I：

10.1107/S0108270196009614

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

The structure determination of the title compound, C12H18NO2+.C8H7O3-, has allowed the absolute configuration of the cation to be established. The demethylated base, (S)-5,6-dihydroxy-1,2,3,4-tetrahydro-2-naphthalenamine, or (2S)-5,6-ADTN, is responsible for the dopaminergic activity; this work shows that it has the same spatial arrangement as (6aR)-apomorphine.

引用

页码：3147 / 3150

页数：4

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