3'-end-forming signals of yeast mRNA

被引:122
作者
Guo, ZJ [1 ]
Sherman, F [1 ]
机构
[1] UNIV ROCHESTER,SCH MED & DENT,DEPT BIOCHEM,ROCHESTER,NY 14642
关键词
D O I
10.1016/S0968-0004(96)10057-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The signals required for forming 3'-ends of mRNAs from the yeast Saccharomyces cerevisiae differ from the corresponding signals of higher eukaryotes. Yeast signals consist of three elements: (1) the efficiency element, which enhances the efficiency of downstream positioning elements; (2) the positioning element, which positions the poly(A) site; and (3) the actual poly(A) site, These three elements are not only necessary, but also sufficient for mRNA 3'-end formation in yeast.
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页码:477 / 481
页数:5
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